1. Aspirin, NSAIDs and acetaminophen act by

A. Inhibiting impulses to brain.

B. Inhibiting the synthesis of prostaglandins.

C. Competitively blocking the neuronal terminal

D. Releasing endorphin

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2. Salicylate intoxication (salicylism) is characterized by the following symptoms, except

A. Nausea, vomiting, fever

B. Tinnitus, decreased hearing, visual changes

C. Fluid and electrolyte deficiencies

D. Hypoventilation Copyright@ www.nursingplanet.com/Quiz

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3. Which of the following statements about Aspirin is TRUE?

A. Aspirin has no ototoxic characteristics

B. Aspirin is least likely to cause gastric irritation.

C. Aspirin should generally be avoided for 1 to 2 weeks before and after surgery

D. enteric-coated Aspirin (Ecospirin) should be chewed or crushed before swallowing.

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4. Which of the following statements is WRONG about NSAIDs?

A. NSAIDs decrease effects of ACE inhibitors.

B. NSAIDs decrease antihypertensive effects

C. NSAIDs increase the risk of bleeding by prolonging the prothrombin time.

D. NSAIDs decrease the serum lithium levels

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5. Which of the following drugs on overdose is known to cause liver failure;

A. Acetaminophen

B. Ibuprofen

C. Piroxicam

D. Ketorelac Copyright@ www.nursingplanet.com/Quiz

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6. Drugs that increase effects of indomethacin are all, EXCEPT:

A. Corticosteroids

B. Salicylates

C. Heparin

D. Antacids

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7. Intravenous (IV) indomethacin is approved for treatment of:

A. Cardiogenic pain

B. Pain associated with gastritis

C. Patent ductus arteriosus in premature infants

D. Trigeminal neuralgia

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8. The enzyme involved in the therapeutic action of NSAIDs is

A. Cyclo-oxygenase

B. Monoamine oxidase

C. Cytochrome

D. Lipocortin-1

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9. A commonly used NSAID, Ibuprofen belongs to the subclass of

A. Salicylates

B. Pyrazolone derivatives

C, Indole derivatives

D. Prpionic acid derivatives

E. Oxicam derivatives

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10. Which of the following agents is associated with high incidence of agrnulocytosis?

A. Phenylbutazone Copyright@ www.nursingplanet.com/Quiz

B. Phenylbutazone

C. Indomethacin

D. Mephanamic acid

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