1. Polydactyly in man is due to

A. Autosomal recessive allele

B. Autosomal dominant allele

C. Sex linked recessive allele

D. Sex linked dominant allele

2. A monosomic abnormality in human is

A. Klinfelter's syndrome

B. Turner's syndrome

C. Edward's syndrome

D. Down's syndrome

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3. A disease found only in males is

A. Gaucher's disease

B. Lesch-Nyhan disease

C. Hunter's disease

D. Fabry's disease

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4. Mental retardation associated with sex chromosomal abnormality is due to

A. Reduction in X-complement

B. Increase in X-complement

C. Moderate increase in Y-complement

D. Large increase in Y-complement

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5. Which of of the following is holandric inheritance?

A. Haemophilia

B. Epidermolysis

C. Webbed toes

D. Turner's syndrome

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6. Probability of male child of haemophilic father and normal mother becoming haemophilic is

A. 0%

B. 25%

C. 50%

D. 100%

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7. Edward's syndrome characterized by mental deficiency is caused by trisomy of chromosome

A. 5

B. 9

C. 15

D. 18

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8. A man is sterile due to improper development of testes which has an additional chromosome X. The condition is

A. Turner's syndrome

B. Huntington's disease

C. Klinfelter's syndrome

D. Marfan's syndrome

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9. A male child with blood group AB is colour blind. His parents could be

A. Father normal vision with blood group A, mother colour blind with blood group AB

B. Father colour blind with group O, mother colourblind with blood group AB

C. Father normal vision with blood group A, mother colourblind with blood group B.

D. Father colourblind with blood group O, mother normal vision with blood group O.

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10. A mother is afflicted by Down's syndrome caused by an extra copy of chromosome21. Father is normal. The chance of offspring affected by the disorder is

A. 100%

B. 75%

C. 50%

D. 25%

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11. Christmas disease is another name of

A. Sleeping sickness

B. Down's syndrome

C. Hepatitis

D. Haemophilia B

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12. The 'Christmas disease' patients lack antihaemophilic factor

A. Homogentisic acid

B. Factor VIII

C. Factor XI

D. Factor IX

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13. Which is NOT true about haemophilia?

A. Bleeder's disease

B. Royal disease

C. X-linked disease

D. Y-linked disorder

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14. One of the genes present exclusively on the X-chromosome in humans is concerned with

A. Baldness

B. Red-green color blindness

C. Facial hair in males

D. Night blindness

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15. Genetic map is one that

A. establishes sites of the gene on a chromosome

B. Establishes the various stages in gene evolution

C. Shows the stages during cell division

D. Shows distribution of various species in region

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